Diagnosis of Pleural TB
in Areas with Adequate Diagnostic Facilities
・Diagnosis of suspected TB empyema
- Always perform thoracentesis to obtain pleural fluid
- AFB smear and gram stain usually sufficient to make diagnosis
・Diagnosis of suspected TB pleurisy
- Thoracentesis to obtain pleural fluid for smear & culture
- Pleural biopsy with histological examination & culture
- Single pleural biopsy has diagnostic yield of 75%; double pleural biopsies have combined yield of 90%