F-4-02-01
ASSESSMENT OF AUTONOMIC FUNCTION IN STROKE PATIENTS BY POWER SPECTRAL ANALYSIS OF HEART RATE VARIABILITY
Juhn Ahn, Joong-Sun Chon, Se-Il Chun, Deog-Young Kim, Kee-Sam Jeong
(Yonsei University, Seoul, Korea)
Purpose: To assess the autonomic function in stroke patients by power spectral analysis of heart rate variability (HRV) during head-up tilt.
Method: We investigated the responses of the frequency components of HRV in 24 normal subjects and 20 stroke patients (10 Lt. hemisphere stroke, 10 Rt. hemisphere stroke). The ECG and respiration signals were recorded at tilt angles of 0゜and 70゜for 5 minutes respectively under the condition of frequency controlled respiration (0.25Hz).
Result: Comparing with normal subjects, stroke patients showed reduced total, low, and high frequency power at 0゜and 70゜tilt angle. Furthermore, they showed an increase in heart rate at 0゜, a decrease in normalized high frequency power at 0゜, and a decreased normalized low frequency power at 70゜(p<.05). Rt. hemisphere stroke patients showed significantly reduced total, low, and high frequency power at 0゜and 70゜compared with Lt. hemisphere stroke patients (p<.05).
Conclusion: Stroke patients, especially involving the Rt. hemisphere showed attenuated autonomic cardiac innervation during head-up tilt.
F-4-02-02
SYMPATHETIC SKIN RESPONSE AND RR INTERVAL VARIATION IN PRIMARY FIBROMYALGIA SYNDROME
Tansu Arasil , Ayse A. Kucukdeveci, Cenk Akbostanci, Sehim Kutlay,(Ankara University, Ankara, Turkey)
It has been suggested that increased sympathetic activity might be a part of the underlying mechanism in primary fibromyalgia syndrome (PFS). Sympathetic skin response (SSR) and RR interval variation (RRIV) are considered as valuable tests in evaluating autonomic system function. In order to evaluate the autonomic function in PFS, SSR and RRIV were performed on 25 patients with PFS and on 23 normal controls. ESAOTE Phases II Electromyography system was used for electrophysiological assessment. Clinical evaluation of the severity of dysautonomia was done by an autonomic nervous system disability scale. The results indicated SSR latencies and amplitudes of hands and feet of PFS patients were not significantly different from that of control group (p>0,05). However SSR from feet could not be recorded in one PFS patient whose hand SSR latencies were also prolonged. RRIV was significantly more decreased after hyperventilation in PFS group than the controls (p<0,05). PFS patients showed higher autonomic disability levels than normal subjects (p<0,0005). These data suggested that although SSR results indicating sympathetic system function was not different from normal subjects, RRIV showing parasympathetic function was disturbed in PFS. We concluded further studies are necessary to determine the exact role of autonomic dysfunction in PFS.
