MIDDLE LATENCY AUDITORY EVOKED PESPONSES (MLRs) AND TOMOGRAPHIC IMAGING OF IODINE-123 ・IMP IN PATIENTS WITH POST-STROKE APHASIA
Syoichiro Tochigi, Mitsunobu Kono-1, Osamu Takahashi-2, Fujiko Hotta-2, Motohide Arita-2, Tetuo Ota-2, Shigeru Sonoda-2, Eiichi Saito-3, Masato kawakami-4 , Toyoaki Sato-4, Tetsumi Honda-2 (1-Tokyo Metropolitan College, 2-Tokyo Metropolitan Rehabilitation Hospital, 3-Fujita health University, Toyoake, 4-St. Marianna University, Kawasaki, Japan)
Purpose: This study was aimed at identifying tile effect on middle latency auditory evoked responses (MLRs) responsible for post-stroke aphasia.
Method: The patients were subdivided to 21 cases with predominantly expressive aphasia and 26 cases with predominantly receptive aphasia. Simultaneous auditory brainstem responses (ABRs) and MLRs were recorded from 46 right-handed and 1 left-handed stroke patients and 19 age-matched hospital control subjects. Thereafter, single-photon emission computad tomography (SPECT) imaging of iodine- 123. IMP was performed of wave deformation cases.
Result: There were 17 cases in which Pa component did not occur with normal amplitude and latency. The lesions of disorganization cases were compatible with reduced IMP uptake areas on the tomographic imaging effecting thalamus to auditory cerebral cortex projection.
Conclusion: The MLRs recording play an important role in diagnosis for aphasia patients with deep and midline cerebro-vascular lesions.
EFFECTS OF HYPERBALIC OXYGENATION TO CHRONIC APHASICS
Manabu KAWATSU, H. KAMITSUCHIHASI, K. KAWAHIRA, N. TANAKA
Dept. Rehab. and Physic. Med., Kagoshima Univ., Japan
The Purpose is to investigate the effect of hyperbolic oxygenation (HBO) to the chronic aphasics with cerebeller vascular disease (CVD).
Subjects: 6 aphasics (52±4.8 yrs), who have gotten CVD for more than 3 months were studied. The types of aphasics were transcortical sensory type (one patient, TCSA), transcortical mixed type (one patient, TCMA), and global type (four patients, GA including one with crossed aphasia).
Methods: HBO (100% O2 2atm, 60 minutes) was performed, once or twice a day, 20-40 times. Before and just after the trial, standard language test of aphasia (SLTA), Kohs' cubic test, and Rey's figure test were checked up.
Results: The patients with TCSA showed the significant improvements in all tests. The crossed aphasics with GA was moderately improved also in all tests. The patient with TCMA was moderately improved in SLTA but in vain in the other tests. One month after the cessation of HBO the same tests were repeated and the three patients with good improvements showed that they maintained good marks.
Discussion: The effects of HBO have usually been stressed on the acute phase. In the present study, HBO was effective even on the chronic phase in patients with mild subcortical aphasia. Although the mechanism of effects of HBO in chronic cases is unknown, saving of the unfunctional neurons around the necrosis will be suggested. Conclusion: HBO will be the challengeable method even in chronic aphasics to support the rehabilitation of the higher cortical function.