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P-2-17-04

REHABILITATION OF PREGNANT WOMEN WITH HEART DISEASES

Sadykov B.G., Zamaleeva R.S., Sadykova L.B.

(Kazan Medical University, Tatarstan, Russia, Kazan).

 

For the rehabilitation of 128 pregnant women with heart diseases and chronic foetus hypoxia and increasing adaptation processes in the mother-placenta-foetus system bioresonance therapy (BRT) was used for the first time in obstetrical practice. BRT was conducted by a pregnant womans own electromagnetic vibrations, which were taken from the pationt body. For the estimation of the BRT effectiveness we resorted to radioimmunological determination of hormones in blood serum of patients before and after BRT. Ultrasound axamination of foetus was conducted before and after BRT. It was established that BRT leads to foetus normal condition and better physical state of pregnant women.

 

P-2-18-01

DISABILITY PREVENTION OF CHRONIC RENAL FAILURE (CRF): EFFECTS OF MILD TO MODERATE EXERCISE ON RENAL FUNCTION IN RATS WITH CRF

Masahiro Kohzuki, Masahiro Kamimoto, Xue-Min Wu, Kazunori Yoshida, Mihoko Watanabe, Tokutaro Sato. (Section of Internal Medicine & Disability Prevention, Tohoku University Graduate School of Medicine, Sendai, Japan)

 

Exercise training, which has some potential for improving cardiovascular and metabolic disorders, is beneficial in the treatment of many chronic disease states including ischemic heart disease, hypertension, diabetes mellitus, and hyperlipidemia. In contrast, acute exercise causes proteinuria and subsequent reductions in both renal blood flow and glomerular filtration rate. The quantity of urinary excretion is known to correlate closely with the extent of histological injury of the glomeruli and patients with chronic renal failure are restricted to mild exercise and tend to lack of exercise. However, there have been few reports regarding the "chronic" influence of exercise on the progression of renal disease. We assessed the renal effects of mild to moderate treadmill exercise in rats remnant kidney model of chronic renal failure (CRF). 8-week-old spontaneously hypertensive rats (SHR) were subjected to 5/6 nephrectomy (SHR-CRF). One week after the operation, the rats were divided into 3 groups: a) no treadmill running; b) mild treadmill running 10m/rain for 30rain (L-Ex); c) moderate treadmill running 20m/rain for 60min (M-Ex) per day for 4 weeks. The effects of chronic infusion of an angiotensin converting enzyme inhibitor, enalapril (2 mg/kg/day i.p.), in combination with M-Ex were also investigated. In SHR-CRF, systolic blood pressure, heart weight, urinary protein excretion, blood urea nitrogen, and serum creatinine level all increased significantly when compared with those of sham-operated SHRs. In SHR-CRF, Neither L-Ex nor M-Ex modified these parameters. In contrast, enalapril significantly attenuated the increase in systolic blood pressure, heart weight, urinary protein excretion, blood urea nitrogen, serum creatinine level. These results were confirmed by morphological analysis of the kidneys in rats with CRF. Enalapril significantly and effectively protected against increases in the glomerular volume and in the percentage of focal glomerular sclerosis. These results suggest that enalapril effectively protects against the progression of experimental renal disease. They also indicate that mild to moderate exercise does not worsen renal function in this model of rats.

 

 

 

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