P-2-06-03
Relationships between Event-related Potentials (P300) and Activities of Daily Living in Parkinson's disease
Mari Nakagawa, Ichiro Kamei (Wakayama Red Cross Medical Center, Wakayama, Japan) Shinichiro Maeshima (University of Sydney), Kunio Nakai, Toru Itakura, Norihiko Komai (Department of Neurological Surgery, Wakayama Medical College, Wakayama, Japan)
The correlation between event-related potentials (P300) and activities of daily living (ADL) was studied in Parkinson's disease. The P300 of 32 patients with Parkinson's disease and 20 normal subjects were recorded. All patients were evaluated by the Mini-mental State (MMS), Kana-hiroi Test, word fluency, Raven's Colored Progressive Matrices (RCPM), Osaka Memory Scale, revised Wechsler Adult Intelligence Scale and Functional Independence Measure (FIM). Thirteen patients showed prolonged P300 latencies. P300 latency showed relationships to the MMS and cognitive items of the FIM. P300 amplitude showed a relationship to performance IQ, RCPM and motor items of the FIM. There was no relationship between P300 and age, disease severity or duration, or dosages of antiparkinsonian drugs. We concluded that P300 should be useful in predicting ADL in patients with Parkinson's disease.
P-2-06-04
TRDICAL RIGIDITY IN PARKINSON'S DISEASE
Hajime Hino, Wataru Onuki, Yohko Dekura. Akira Yamaguchi (National Center of Neurology and Psychiatry. Tokyo, Japan)
PURPOSE: Truncal rigidity causes a Parkinson's patient difficulty in normal daily activities such as turning around, standing up, and sitting down. The degree of difficulty which the patient experiences can be quantified by measuring the responses to passive movements that are of a well defined range and speeds.
METHOD: To study this, the resistant torque during passive isokinetic truncal extension and flexion was recorded together with rectified surface EMG from agonistic and antagonistic muscle. The movements were controlled by an isokinetic dynamometer that quantifies the torque of resistance at constant speed. Electrical activities of the truncal muscles, (M. erector spinae, Rectus muscle of abdomen) during the alternating truncal tilts were studied.
PARTICIPANTS: Normal adults and patients with Parkinson's disease were examined.
RESULTS: Continuous electrical activities were present in the axial muscles. When the trunk begins an extension from a flexion, the Parkinson's patients torque curve falls slowly, while in a normal subject it falls rapidly.
CONCLUSIONS: The results suggest that Parkinson's patients cannot stretch their trunks easily. This method is useful to evaluate the truncal rigidity objectively.
