Activities of daily living in patients with Parkinson's disease: Influence of motor and cognitive functions
Yasuhiko Nishimura, Shinichiro Maeshima, Mari Nakagawa, Hiroki Nishibayashi, Kunio Nakai, Toru Itakura, Norihiko Komai
Department of Neurological Surgery, Wakayama Medical College, Japan
Rehabilitation Studies, University of Sydney & Royal Rehabilitation Centre
The aim of this study was to investigate the correlation between motor and cognitive function and activities of daily living (ADL) in Parkinson's disease (PD). In forty patients with PD, neurologic and neuropsychologic testing were performed, and ADL were examined. Motor function performance correlated highly with neuropsychologic testing. A significant correlation also was found between ADLs and motor and cognitive functions. Following a stepwise regression analysis to assess the significance of each of the factors that determine the ADL score, three factors - performance IQ, verbal IQ, and pronation-supination test- were revealed to have the greatest impact on ADLs in PD. Our results suggest that cognitive dysfunction is an important factor determining performance of ADL in PD.
IMPAIRMENT INFLUENCING ON DETERIORATION OF ADL IN PATIENTS WITH PARKINSON'S DISEASE
Jun-ichi Kitamura (Nippon Medical School, Kawasaki, Japan), Ryohei Koga, Toshihiko Hamada (Tokyo Fukushi Gakuen, Tokyo, Japan)
Yahr stage of Parkinson's disease consists of stages I-III evaluated by impairment and stage IV-V evaluated by disability. The present study aimed to investigate which kinds of impairment influence on deterioration of disability. 45 Parkinson's disease patients, mean age of 70.5 year-old, were studied. Patients in stage III had more impaired righting reflex and abnormal posture than those in stage II, and those in stage IV more impaired turn and righting reflex than those in stage III, and patients in stage V more akfnseia, gait disturbance and speech disturbance (dyspahgia) than those in stage V. Akinesia and impaired righting reflex and turn are more influencing factros on deterioration of ADL in patients with Parkinson's disease than tremor or rigidity.