Patient Variables
Forgetfulness
Competing sociocultural and ethnic folk concepts of disease/treatment.
Apathy, pessimism, depression
Health beliefs; denial of illness.
Lack of social supports.
Residential instability.
Dissatisfaction with practitioner and/or treatment.
Sensory disabilities.
Previous history of non-adherence.
Competing or conflicting demands.
Parents expectations and attitude toward treatment.
Lack of resources.
Inability to follow treatment plans.
Treatment Variables
Complexity of treatment regimen.
Long duration of treatment.
Degree of behavioral change required.
Expense
Characteristics of medicine.
Medication side effects.
Medication interaction with food or other drugs.
Awkward medication container design.
Timing or referral.