Is DOTS Based on Sound Scientific Principles?
・Case detection by sputum microscopy enables identification of 80-90% of infectious sources
・Case-finding among symptomatic patients self-reporting to health services is much more cost-effective than active case-finding
・Use of standardized short-course treatment regimens is based on available scientific information
・Use of DOT shown to improve patient adherence to treatment
Is DOTS Built on Successful Field Experience?
・Originally developed in Africa during the 1980s
・Has been successfully implemented in over 100 countries
・Shown to work under diverse conditions and environments; can be adapted to specific situations
・The use of DOT, treatment regimens, and recording and reporting system has been applied to many countries
