Clinical Development of TB (2)

　

・Factors important for disease risk: Balance between Virulence and Resistance (immunity and nature)

- Infection with close contact and from heavily positive patient

- Age: young infancy and adolescence (but, old age?)

- Immunocompromized hosts: HIV/AIDS, Diabetes, Hemodialysis

- Silicosis, Corticosteroid therapy,...

- Natural resistance: Nutrition

- Genetic traits: Lean & tall body type, gastric ulcer, specific genes?

- Psychological stress

　

Risk Factors of Tuberculosis Development

(Relative Risk, adapted from Rieder et al)

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