22. Granuloma multiforme. This condition, which clearly mimics leprosy to a remarkable degree, was originally described, and occurs mainly in Nigeria, but has occasionally been found elsewhere. Its cause is unknown; possibly a variant of granuloma annulare (see picture 14). lnitial stages are characterised by itching (not typical for leprosy). Lesions disappear sooner or later and do not respond to any from of treatment. Sensation, sweating and peripheral nerves - all normal.