SP-3-02-D-03
EVALUATION OF REGIONAL CEREBRAL BLOOD FLOW IN APHASIC PATIENTS USING STABLE XE-ENHANCED CT
Haruo Inada, Masako Yamazaki, Ken Sasaki (Chiba Rehabilitation Center, Chiba, Japan)
The purpose of this study is to predict the prognosis of aphasia by regional cerebral blood flow (rCBF) patterns measured by stable Xe-enhanced CT (Xe-CT).
The 115 aphasic patients, mostly from stroke, were examined by Xe-CT and Standard Language Test of Aphasia(SLTA)just after admission to our hospital. They were divided into two groups: l) the fresh group, in which the average period from the onset to rCBF study was around 133 days, and 2) the chronic group, in which that period was 387-5703 days. The severity of aphasia was classified to two grades according to the result of SLTA.
The rCBF patterns were classified to three groups: i) low CBF of the right hemisphere, ii) normal CBF of the right hemisphere + low CBF of the left parietal white matter, and iii) normal CBF of both the right hemisphere and the left parietal white matter.
The correlation between the severity of aphasia and the rCBF patterns revealed that in i) and ii) groups of rCBF patterns, the grade of aphasia was significantly severe, whereas in iii) group, the aphasia recovered significantly well.
From this result, we speculated that the recovery from aphasia depends largely on the compensation of the right hemispheric function at least in fresh stage from the onset, and such compensation is achieved through the trans-hemispheric fiber connection passing in the parietal white matter.
SP-3-02-E-01
RELATIONSHIP BETWEEN 'H-MRS AND DYSARTHRIC SPEECH IN SCD PATIENTS
Makiyo Kubo, Nobuko Goi, Katsuyushi Isonishi, Susumu Kawaguchi, and Takeshi Kashiwaba (Kashiwaba Neurosurgical Hospital, Sapporo, Japan)
The purpose of the present study was to assess the relationship between the characteristics and the severity of dysarthfia and brain metabolism in patients with spinocerebellar degeneration (SCD), using acoustic analysis and proton magnetic resonance spectroscopy ('H-MRS).
Methods: N-acetyl-L-aspartate (NAA) in the cerebellum was measured by 'H-MRS. Speech samples were obtained by using repeated utterance tasks of/pa/,/ta/and/ka/. The voice onset time (VOT), number of syllable repetitions per second, and syllabic duration time were measured using soundspectroscopy.
Results and conclusions: The results indicated that as the amount of NAA decreased, the number of syllable repetitions became smaller, and the variability of VOT and syllabic duration time became larger.
