P-2-15-03
FUNCTIONAL OUTCOME OF SPINAL EPIDURAL NON-HODGKIN'S LYMPHOMA
Koji Ugawa, Koichiro Hayashi (University of Tsukuba, Tsukuba, Japan)
Abstract: We report a retrospective study of primary or secondary spinal epidural non-Hodgkin's lymphoma, analyzing the factors influencing functional outcome. Between 1988 and 1996, three patients with primary spinal lymphoma and four patients with secondary spinal lymphoma were referred to our department. They were five males and two females with the age of 23 to78 years. The mean follow-up was 15 months (5-27 months). All patients had clinical stage IV. The site of cord compression was cervical in one, thoracic in four and lumbosacral in two patients. Histologically, the tumor proved to be a intermediate- grade in six patients and high-grade in One. The treatment was physical therapy and chemotherapy in all patients and radiotherapy in six and surgery in three patients. Regarding functional status, three patients were paraplegic, four patients were able to move legs but unable to walk before treatment. Following treatment, the four patients who had been able to move legs were able to walk with aid, the status of three paraplegic patients were unchanged. It appears that functional outcome is related to functional status prior to treatment.
P-2-16-01
EFFECT OF RESPIRATORY ASSIST MANEUVER ON VENTILATION AND METABOLISM IN PATIENTS WITH SEVERE CEREBRAL PALSY
Satoru Hirano, Yumi Ohgoshi, Akira Yamaguchi, Sachio Takashima (National Center of Neurology and Psychiatry, Tokyo, Japan)
PURPOSE; The purpose of the present study was to evaluate the effect of respiratory assist maneuver performed as pulmonary rehabilitation for patients with severe cerebral palsy.
METHOD: O2 consumption (VO2), CO2 production (VCO2), Ventilation (VE) were measured during respiratory assist maneuver using a telemetric system (AT-1000; Anima Co.) in 6 cases of severe cerebral palsy as well as in 6 normal subjects.
RESULTS: VE, VCO2, and tidal volume were increased during respiratory assist in normal subjects. On the other hand VE, VO2, VCO2 were decreased in patients with cerebral palsy who had scoliosis and decreased mobility of the thoracic cage.
CONCLUSION: The effect of respiratory assist maneuver was similar to mild hyperventilation in normal subjects. In patients with severe cerebral palsy however, respiratory assist maneuver decreased energy consumption wasted in respiration and facilitated a greater respiratory movement.